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LUX CAPITAL
The Lux Bio + Tech Index

LUXBT

$LUXBT

Index Performance

-2.64%
LUXBT
+3.30%
SP500
-2.09%
ICEBIOT
+0.96%
SPSIBITR

Overview

Description

Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingCustom
  • # of holdings54
What's inside?

Holdings

All holdings as of December 8, 2023
CSV download
BridgeBio Pharma, Inc. (BBIO)9.50%$5.657B1,110.36%52.65%582.88x
Third Harmonic Bio, Inc. (THRD)4.73%$401.608MN/AN/AN/A
Nuvalent, Inc. (NUVL)4.63%$4.041BN/AN/AN/A
Schrödinger, Inc. (SDGR)3.90%$2.009B15.11%55.53%8.32x
10X Genomics, Inc. (TXG)3.21%$5.087B17.22%56.08%7.78x
Recursion Pharmaceuticals, Inc. (RXRX)2.93%$1.583B-19.96%-35.55%27.48x
Tango Therapeutics, Inc. (TNGX)2.70%$936.265M55.09%94.29%20.57x
CRISPR Therapeutics AG (CRSP)2.68%$5.127B-100.00%N/A12.39x
Evotec SE (EVO)2.64%$3.492B21.97%19.27%4.39x
Ionis Pharmaceuticals, Inc. (IONS)2.45%$6.986B-9.74%94.60%10.14x
Editas Medicine, Inc. (EDIT)2.42%$858.391M12,604.76%71.63%13.08x
Certara, Inc. (CERT)2.30%$2.626B1.03%44.61%6.64x
Alector, Inc. (ALEC)2.23%$514.915M-38.67%75.22%-0.05x
Dyne Therapeutics, Inc. (DYN)2.11%$686.179MN/AN/AN/A
Exscientia Plc (EXAI)2.11%$686.137M51.81%-25.17%4.59x
Verve Therapeutics, Inc. (VERV)2.10%$1.005B235.52%-2.63%56.36x
Sana Biotechnology, Inc. (SANA)2.10%$733.336MN/AN/AN/A
Regeneron Pharmaceuticals, Inc. (REGN)2.10%$90.003B14.53%83.89%6.57x
Caribou Biosciences, Inc. (CRBU)2.09%$513.785M616.38%91.10%2.58x
Nurix Therapeutics, Inc. (NRIX)1.89%$417.132M71.13%81.68%3.08x
Janux Therapeutics, Inc. (JANX)1.84%$415.978M38.83%80.14%16.05x
Nkarta, Inc. (NKTX)1.78%$133.967MN/AN/AN/A
Nuvation Bio, Inc. (NUVB)1.77%$291.196MN/AN/AN/A
Olink Holding AB (OLK)1.76%$3.189B40.54%69.96%10.88x
ATAI Life Sciences NV (ATAI)1.76%$200.873M262.50%14.94%32.58x
Roivant Sciences Ltd. (ROIV)1.62%$7.903B196.03%78.03%81.99x
Intellia Therapeutics, Inc. (NTLA)1.59%$2.599B-9.60%80.90%39.92x
Denali Therapeutics, Inc. (DNLI)1.59%$2.539B-64.40%-74.98%5.24x
Compass Pathways Plc (CMPS)1.42%$400.395MN/AN/AN/A
Ginkgo Bioworks Holdings, Inc. (DNA)1.36%$2.202B-16.52%42.02%9.15x
Arvinas, Inc. (ARVN)1.28%$1.880B14.19%95.09%0.39x
Kymera Therapeutics, Inc. (KYMR)1.26%$1.276B-50.50%80.96%11.42x
Revolution Medicines, Inc. (RVMD)1.25%$4.028B-100.00%N/A86.87x
SomaLogic, Inc. (SLGC)1.17%$460.377M-47.14%47.23%-0.03x
Lyell Immunopharma, Inc. (LYEL)1.09%$483.588M733.33%-20,316.00%-2.91x
Beam Therapeutics, Inc. (BEAM)1.07%$2.152B8.82%56.52%12.99x
Century Therapeutics, Inc. (IPSC)1.05%$142.407M-93.35%-1,107.43%-1.22x
Ultragenyx Pharmaceutical, Inc. (RARE)1.02%$3.322B8.10%88.79%7.47x
Relay Therapeutics, Inc. (RLAY)1.00%$1.155B7,226.16%94.59%10.54x
4D Molecular Therapeutics, Inc. (FDMT)0.99%$638.739M3,940.80%93.09%10.62x
SAGE Therapeutics, Inc. (SAGE)0.96%$1.200B56.18%66.68%32.07x
Fate Therapeutics, Inc. (FATE)0.94%$220.868M-87.02%-143.83%-0.34x
AbCellera Biologics, Inc. (ABCL)0.93%$1.413B-93.49%-12.27%11.94x
Stoke Therapeutics, Inc. (STOK)0.93%$212.999M13.87%63.72%-4.00x
ProKidney Corp. (DNAC)0.93%$120.846MN/AN/AN/A
Vir Biotechnology, Inc. (VIR)0.91%$1.294B-99.30%-144.07%-2.73x
BioNTech SE (BNTX)0.89%$25.135B-72.05%81.93%1.74x
Alnylam Pharmaceuticals, Inc. (ALNY)0.88%$21.339B183.96%88.77%13.64x
Adaptive Biotechnologies Corp. (ADPT)0.81%$681.880M-20.72%33.78%3.61x
Prime Medicine, Inc. (PRME)0.78%$827.257MN/AN/AN/A
Moderna, Inc. (MRNA)0.77%$30.625B-44.75%-35.99%3.66x
Erasca, Inc. (ERAS)0.74%$282.533MN/AN/AN/A
Seer, Inc. (California) (SEER)0.69%$102.224M5.23%15.81%-10.02x
Seres Therapeutics, Inc. (MCRB)0.35%$140.890M-91.00%-1,153.87%2.73x
Market data by FactSet