| Alnylam Pharmaceuticals, Inc. (ALNY) | 29.20% | $62.53B | 149.35% | 83.98% | 19.53 |
| BioNTech SE (BNTX) | 10.94% | $23.26B | 29.80% | 90.24% | 2.01 |
| BridgeBio Pharma, Inc. (BBIO) | 6.67% | $14.29B | 4,318.01% | 93.98% | 34.01 |
| Ionis Pharmaceuticals, Inc. (IONS) | 6.14% | $13.26B | 17.12% | 96.67% | 10.60 |
| Avidity Biosciences, Inc. (RNA) | 4.92% | $10.79B | 434.03% | 91.54% | 200.41 |
| BioMarin Pharmaceutical, Inc. (BMRN) | 4.91% | $10.43B | 5.98% | 81.58% | 3.09 |
| Moderna, Inc. (MRNA) | 4.61% | $9.84B | -45.44% | 74.51% | 2.82 |
| Arrowhead Pharmaceuticals, Inc. (ARWR) | 4.23% | $8.84B | 23,258.15% | 97.12% | 5.38 |
| PTC Therapeutics, Inc. (PTCT) | 2.83% | $6.08B | 7.23% | 88.95% | 2.29 |
| CRISPR Therapeutics AG (CRSP) | 2.40% | $5.34B | 47.67% | -6,819.57% | 109.80 |
| Arcellx, Inc. (ACLX) | 1.90% | $4.22B | -80.99% | 62.76% | 118.01 |
| Genscript Biotech Corp. (1548) | 1.90% | $4.04B | -28.87% | 46.20% | 3.81 |
| Ultragenyx Pharmaceutical, Inc. (RARE) | 1.65% | $3.52B | 14.65% | 77.12% | 5.45 |
| Amicus Therapeutics, Inc. (FOLD) | 1.42% | $3.02B | 19.46% | 87.38% | 4.38 |
| Beam Therapeutics, Inc. (BEAM) | 1.27% | $2.71B | -32.03% | 42.67% | 28.11 |
| Sarepta Therapeutics, Inc. (SRPT) | 1.00% | $2.29B | -14.52% | 57.63% | 0.97 |
| ImmunityBio, Inc. (IBRX) | 0.98% | $2.17B | 425.07% | 87.12% | 35.53 |
| 10X Genomics, Inc. (TXG) | 0.96% | $2.26B | -1.75% | 67.71% | 1.67 |
| Twist Bioscience Corp. (TWST) | 0.89% | $1.91B | 20.32% | 50.72% | 4.05 |
| Oxford Nanopore Technologies Plc (ONT) | 0.79% | $1.70B | 7.97% | 44.46% | 4.72 |
| uniQure NV (QURE) | 0.66% | $1.57B | 61.83% | -8.89% | 206.53 |
| Capricor Therapeutics, Inc. (CAPR) | 0.64% | $1.37B | -100.00% | N/A | 22.37 |
| CanSino Biologics, Inc. (CASBF) | 0.56% | $1.50B | 18.16% | 78.37% | 10.58 |
| CureVac NV (CVAC) | 0.55% | $1.16B | -88.34% | 91.57% | 9.49 |
| Sana Biotechnology, Inc. (SANA) | 0.54% | $1.19B | N/A | N/A | N/A |
| Wave Life Sciences Ltd. (WVE) | 0.53% | $1.19B | N/A | 70.69% | 9.70 |
| Precigen, Inc. (PGEN) | 0.50% | $1.26B | 206.61% | 53.70% | 156.55 |
| Oxford Biomedica Plc (OXB) | 0.47% | $1.01B | 43.84% | 40.65% | 3.77 |
| Intellia Therapeutics, Inc. (NTLA) | 0.46% | $1.05B | 51.27% | 64.19% | 25.90 |
| Arbutus Biopharma Corp. (ABUS) | 0.40% | $852.00M | -60.49% | 97.92% | 53.51 |
| Iovance Biotherapeutics, Inc. (IOVA) | 0.38% | $877.30M | 15.20% | 29.61% | 2.16 |
| Graphite Bio, Inc. (GRPH) | 0.38% | $797.61M | N/A | 99.00% | 64.47 |
| MeiraGTx Holdings Plc (MGTX) | 0.31% | $653.59M | -96.24% | -746.10% | 26.97 |
| REGENXBIO, Inc. (RGNX) | 0.31% | $652.03M | 22.88% | 67.68% | 3.05 |
| Gevo, Inc. (GEVO) | 0.27% | $564.58M | 2,073.54% | 29.38% | 4.37 |
| Maravai Lifesciences Holdings, Inc. (MRVI) | 0.24% | $897.53M | -36.15% | 12.14% | 3.78 |
| 4D Molecular Therapeutics, Inc. (FDMT) | 0.24% | $611.35M | 2,900.00% | -2,125.56% | 1,707.82 |
| Absci Corp. (ABSI) | 0.23% | $494.72M | -77.78% | -651.85% | 97.50 |
| Ginkgo Bioworks Holdings, Inc. (DNA) | 0.20% | $545.92M | -56.39% | 30.56% | 4.23 |
| Solid Biosciences, Inc. (SLDB) | 0.19% | $404.35M | N/A | N/A | N/A |
| Entrada Therapeutics, Inc. (TRDA) | 0.18% | $384.87M | -91.75% | 25.65% | -0.55 |
| AVROBIO, Inc. (AVRO) | 0.18% | $392.58M | N/A | N/A | N/A |
| Cellectis SA (ALCLS) | 0.16% | $338.76M | 104.10% | 85.76% | 2.66 |
| Allogene Therapeutics, Inc. (ALLO) | 0.16% | $341.59M | N/A | N/A | N/A |
| Benitec Biopharma, Inc. (BNTC) | 0.16% | $425.99M | N/A | N/A | N/A |
| Abeona Therapeutics, Inc. (ABEO) | 0.11% | $256.33M | N/A | N/A | 257.63 |
| Voyager Therapeutics, Inc. (VYGR) | 0.11% | $235.19M | -45.73% | 93.03% | 3.32 |
| Carbios SA (ALCRB) | 0.10% | $215.67M | 466.67% | N/A | 482.21 |
| Editas Medicine, Inc. (EDIT) | 0.10% | $230.87M | 12,265.57% | 90.44% | 4.87 |
| ProQR Therapeutics NV (PRQR) | 0.10% | $211.48M | -20.23% | 76.72% | 6.80 |
| Arcturus Therapeutics Holdings, Inc. (ARCT) | 0.08% | $187.24M | -63.54% | 94.35% | 3.43 |
| Caribou Biosciences, Inc. (CRBU) | 0.08% | $173.85M | 8.60% | 71.29% | 10.28 |
| PepGen Inc. (PEPG) | 0.08% | $360.93M | N/A | N/A | N/A |
| Codexis, Inc. (CDXS) | 0.07% | $152.65M | -32.98% | 56.02% | 4.34 |
| Sangamo Therapeutics, Inc. (SGMO) | 0.07% | $168.01M | -98.82% | -226.68% | 6.08 |
| Fate Therapeutics, Inc. (FATE) | 0.06% | $124.58M | -43.36% | -85.35% | 1.93 |
| Atlantic International Corp. (SQL) | 0.05% | $111.20M | 2.16% | 9.80% | 0.55 |
| Aemetis, Inc. (AMTX) | 0.05% | $106.88M | -27.32% | -0.10% | 3.12 |
| Agronomics Ltd. (AGNMF) | 0.04% | $96.22M | N/A | N/A | N/A |
| Kraig Biocraft Laboratories, Inc. (KBLB) | 0.04% | $90.25M | N/A | N/A | N/A |
| Atara Biotherapeutics, Inc. (ATRA) | 0.04% | $90.49M | -91.41% | 96.67% | 1.57 |
| Adverum Biotechnologies, Inc. (ADVM) | 0.04% | $92.06M | -100.00% | N/A | N/A |
| Calyxt, Inc. (CLXT) | 0.04% | $84.63M | -63.11% | -126.67% | 80.52 |
| Precision BioSciences, Inc. (DTIL) | 0.03% | $121.80M | -97.74% | -5,084.62% | 70.91 |
| Vor Biopharma, Inc. (VOR) | 0.03% | $186.46M | N/A | N/A | N/A |
| Senti Biosciences, Inc. (SNTI) | 0.03% | $57.84M | N/A | N/A | N/A |
| Adicet Bio, Inc. (ACET) | 0.02% | $82.30M | N/A | N/A | N/A |
| Atlas Energy Corp. (CANSF) | 0.02% | $44.13M | -100.00% | N/A | 21.72 |
| Generation Bio Co. (GBIO) | 0.02% | $35.24M | -78.90% | 11.92% | -1.46 |
| Dyadic International, Inc. (DYAI) | 0.02% | $34.10M | -40.50% | 12.07% | 10.63 |
| Passage Bio, Inc. (PASG) | 0.01% | $26.80M | N/A | N/A | N/A |
| Gensight Biologics SA (GSGTF) | 0.01% | $23.52M | 18.39% | N/A | 25.20 |
| Celyad Oncology SA (CYAD) | <0.01% | $9.67M | 82.35% | 494.09% | 230.29 |
| Evogene Ltd. (EVGN) | <0.01% | $9.24M | -84.27% | -40.38% | 2.19 |
| Alaunos Therapeutics, Inc. (TCRT) | <0.01% | $7.95M | N/A | N/A | 553.85 |
| Mustang Bio, Inc. (MBIO) | <0.01% | $8.69M | N/A | N/A | N/A |
| Phio Pharmaceuticals Corp. (PHIO) | <0.01% | $13.89M | N/A | N/A | N/A |
| EvoNext Holdings SA (EVE) | <0.01% | $6.78M | -100.00% | N/A | N/A |
| Percheron Therapeutics Ltd. (ATHJF) | <0.01% | $5.75M | N/A | N/A | N/A |
| Arcadia Biosciences, Inc. (RKDA) | <0.01% | $5.03M | -15.29% | 32.10% | -0.22 |
| BacTech Environmental Corp. (BAC) | <0.01% | $4.15M | N/A | N/A | N/A |
| AquaBounty Technologies, Inc. (AQB) | <0.01% | $3.84M | -100.00% | N/A | N/A |
| Sorrento Therapeutics, Inc. (SRNE) | <0.01% | $2.26M | 18.78% | N/A | 7.21 |
| Digital Asset Technologies, Inc. (EATS) | <0.01% | $0.94M | 192.46% | 100.00% | 360.72 |
| Cult Food Science Corp. (CULT) | <0.01% | $0.67M | N/A | -308.89% | 431.00 |
| Bio-Path Holdings, Inc. (BPTH) | <0.01% | $0.61M | N/A | N/A | N/A |
| MediGene AG (MDG1) | <0.01% | $0.52M | -80.69% | N/A | 3.93 |
